A man who was seen ‘acting irrationally’ in Custom House has died in hospital after being handcuffed by police.

Newham Recorder: A cordon is in place on Prince Regent Lane. Picture: Jioji LaisaniA cordon is in place on Prince Regent Lane. Picture: Jioji Laisani (Image: Archant)

Officers were initially called to Cundy Road at 7.15am today (Wednesday, July 31) to reports of a man assaulting people in the middle of the road.

It was then reported that he walked off towards Prince Regent Lane and was seen throwing himself onto passing cars and confronting council workers.

He then ran towards the ExCeL, where police found him being restrained by security staff.

Officers handcuffed the man, believed to be 37, but he became unresponsive.

He was given first aid until the London Ambulance Service arrived and took him to hospital, where he died a short while later.

Police are in the process of informing his next of kin.

Cordons are in place in both Prince Regent Lane and at the ExCeL, and road closures are in place.

A member of ExCeL security staff was treated at hospital for bite injuries.

The Directorate of Professional Standards has been informed, and enquiries continue.

A newsagent, who asked not to be named, said that the man had visited his shop at about 7am that morning, but hadn't bought anything.

"He was distressed," the 27-year-old said. "He comes in sometimes. He seemed like a normal guy. It's sad.

"He always comes alone. He was usually a quiet guy, not talking much. It was the same today."

A 43 year old woman who lives in Cundy Road said: "It makes me feel unsafe. For this to happen on our own doorsteps is shocking."

Another woman, 19, added: "It's not normally like this so when something like this happens it takes everyone by surprise."