Carpenters Estate residents were frustrated after planned talks with Olympic legacy chiefs were cancelled.
A meeting had been lined up for Friday with Daniel Moylan, chairman of the London Legacy Development Corporation.
Members of Carpenters Against Regeneration Plans (CARP) wanted to discuss concerns over plans to transform the Stratford site into a University College London (UCL) campus.
But London Mayor Boris Johnson last week moved Mr Moylan to a new role looking after his aviation policy after just three months in the job. It was reported that he did not get on with fellow members of the board.
Mr Johnson will now occupy the role of LLDC chairman himself.
Joe Alexander, vice chairman of CARP, said: “We are extremely disappointed that our meeting has been cancelled at the last hour.
“We had high hopes that the LLDC and Boris Johnson would honour their commitment of ensuring that the Olympic Legacy would include local communities.”
The UCL is expected to finally unveil its proposals for the site to Newham Council next month.
CARP has now been advised to contact Dennis Hone, the chief executive of the corporation, with its concerns.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here